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Therapy Name | Doxycycline + Metformin |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Doxycycline | Alti-Doxycycline | Doxcycline anhydrous | ||
Metformin | Glucophage | Apo-Metformin | mTOR Inhibitor 51 | Glucophage (metformin) inhibits part of the mitochondrial respiratory chain and may exert antineoplastic effects through inhibition of mTOR and is FDA approved for type 2 diabetes (FDA.gov). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT02874430 | Phase II | Doxycycline + Metformin | Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer | Active, not recruiting | USA | 0 |
NCT03076281 | Phase II | Doxycycline Doxycycline + Metformin Metformin | Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | Active, not recruiting | USA | 0 |