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ID DOID:3571
Name liver cancer
Definition A hepatobiliary system cancer that is located_in the liver.
Source DiseaseOntology.org
Alt Ids DOID:12300 DOID:269 DOID:919 DOID:915 DOID:7330
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer hepatobiliary system cancer liver cancer

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
NRAS mutant Trametinib liver cancer sensitive detail...
CTNNB1 mut NRAS mut Trametinib liver cancer resistant detail...
NRAS Q61L ERAS-007 liver cancer sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01071941 Phase I Oncolytic HSV-1 rRp450 rRp450-Phase I Trial in Liver Metastases and Primary Liver Tumors Terminated USA 0
NCT01497444 Phase Ib/II Evofosfamide + Sorafenib Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery Completed USA 0
NCT01625351 Phase I Fludarabine Melphalan Busulfan Alemtuzumab A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas Completed USA 0
NCT01829971 Phase I MRX34 A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection Terminated USA 1
NCT02795156 Phase II Cabozantinib Afatinib Regorafenib Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations Completed USA 0
NCT02828124 Phase Ib/II BMS-986183 BMS-986183 + Nivolumab A Study of the Safety and Tolerability of BMS-986183 in Patients With Liver Cancer Terminated CAN 3
NCT02932956 Phase I Cyclophosphamide + Fludarabine Anti-GPC3-scFvGC33-CAR autologous T Lymphocytes Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP) (GAP) Active, not recruiting USA 0
NCT03199586 Phase I NP-G2-044 Phase 1 Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Solid Tumors (Including Lymphoma) Completed USA 0
NCT03329950 Phase I CDX-1140 + CDX-301 CDX-1140 A Study of CDX-1140 as Monotherapy or in Combination in Patients With Advanced Solid Tumors Completed USA 0
NCT04430842 Phase I QBS10072S Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S Completed AUS 0
NCT04634357 Phase Ib/II ET140203 ET140203 T-Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma (ARYA-2) Recruiting USA 0
NCT05411133 Phase I ARB202 + Atezolizumab ARB202 Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients Recruiting AUS 1
NCT05947474 Phase I ORB-011 ORB-011 In Patients With Advanced Solid Tumors (ORB) Recruiting USA 0
NCT05964361 Phase Ib/II IL15-TransDC First-in-human Interleukin-15-transpresenting Wilms' Tumor Protein 1-targeting Autologous Dendritic Cell Vaccination in Cancer Patients Recruiting BEL 0