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ID | DOID:8761 |
Name | acute megakaryocytic leukemia |
Definition | An acute myeloid leukemia that derives from blood-forming tissue in which megakaryocytes proliferate in the bone marrow and circulate in the blood in large numbers. |
Source | DiseaseOntology.org |
Alt Ids | DOID:9009 |
Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia acute myeloid leukemia acute megakaryocytic leukemia |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
KIT wild-type | Avapritinib | acute megakaryocytic leukemia | decreased response | detail... |
JAK2 V617F | Ropeginterferon | acute megakaryocytic leukemia | sensitive | detail... |
JAK2 V617F | AZ960 | acute megakaryocytic leukemia | sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT02530619 | Phase I | Alisertib | Alisertib in Treating Patients With Myelofibrosis or Relapsed or Refractory Acute Megakaryoblastic Leukemia | Unknown status | USA | 0 |