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Drug Name | PRT1419 |
Trade Name | |
Synonyms | PRT 1419|PRT-1419 |
Drug Descriptions |
PRT1419 is an inhibitor of myeloid cell leukemia 1 (MCL1) that blocks inactivation of pro-apoptotic proteins by Mcl1, which may lead to apoptosis of tumor cells overexpressing Mcl1 (NCI Drug Dictionary). |
DrugClasses | MCL1 Inhibitor 18 |
CAS Registry Number | NA |
NCIT ID | C176964 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Belzutifan + PRT1419 | Belzutifan PRT1419 | 1 | 0 |
Cabozantinib + PRT1419 | Cabozantinib PRT1419 | 1 | 0 |
Everolimus + PRT1419 | Everolimus PRT1419 | 1 | 0 |
Pazopanib + PRT1419 | PRT1419 Pazopanib | 1 | 0 |
PRT1419 | PRT1419 | 1 | 3 |
PRT1419 + Sunitinib | PRT1419 Sunitinib | 2 | 0 |