Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name PRT1419
Trade Name
Synonyms PRT 1419|PRT-1419
Drug Descriptions

PRT1419 is an inhibitor of myeloid cell leukemia 1 (MCL1) that blocks inactivation of pro-apoptotic proteins by Mcl1, which may lead to apoptosis of tumor cells overexpressing Mcl1 (NCI Drug Dictionary).

DrugClasses MCL1 Inhibitor 18
CAS Registry Number NA
NCIT ID C176964

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Belzutifan + PRT1419 Belzutifan PRT1419 1 0
Cabozantinib + PRT1419 Cabozantinib PRT1419 1 0
Everolimus + PRT1419 Everolimus PRT1419 1 0
Pazopanib + PRT1419 PRT1419 Pazopanib 1 0
PRT1419 PRT1419 1 3
PRT1419 + Sunitinib PRT1419 Sunitinib 2 0


Additional content available in CKB BOOST