Pazopanib
Drug Detail
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| Drug Name | Pazopanib |
| Trade Name | Votrient |
| Synonyms | GW-786034 |
| Drug Descriptions |
Votrient (pazopanib) inhibits VEGFR-1, -2 and -3, KIT, and PDGFR, and FGFR1, 2, and 3, leading to decreased tumor angiogenesis and growth (PMID: 17620431, PMID: 23786770). Votrient (pazopanib) is approved for renal cell carcinoma and soft tissue sarcoma (FDA.gov). |
| DrugClasses | FGFR1 Inhibitor 28 FGFR2 Inhibitor 24 FGFR3 Inhibitor 21 KIT Inhibitor 57 PDGFR Inhibitor (Pan) 30 VEGFR Inhibitor (Pan) 36 |
| CAS Registry Number | 444731-52-6 |
| NCIT ID | C74547 |
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