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Drug Name ART0380
Trade Name
Synonyms ART-0380|ART 0380
Drug Descriptions

ART0380 inhibits ATR activity leading to decreased phopshorylation of Chk1, which may result in impaired DNA damage repair, induction of apoptosis in tumor cells, and antitumor activity (NCI Drug Dictionary, (Ann Oncol 34 (2023): S475-S476).

DrugClasses ATR Inhibitor 16
CAS Registry Number NA
NCIT ID C179292

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ART0380 ART0380 5 2
ART0380 + Gemcitabine ART0380 Gemcitabine 0 1


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