TNB-486
Drug Detail
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| Drug Name | TNB-486 |
| Trade Name | |
| Synonyms | TNB486|TNB 486|AZD0486|AZD-0486|AZD 0486|Surovatamig |
| Drug Descriptions |
TNB-486 is a bispecific T-cell redirecting antibody that binds to CD19 on tumor cells as well as CD3, and may lead to tumor cell killing and inhibition of tumor growth (Blood (2019) 134 (Supplement_1): 4070). |
| DrugClasses | CD19 Antibody 21 CD3 Antibody 119 |
| CAS Registry Number | NA |
| NCIT ID | C178577 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Acalabrutinib + TNB-486 | Acalabrutinib TNB-486 | 0 | 1 |
| Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + TNB-486 + Vincristine Sulfate | Cyclophosphamide Doxorubicin Prednisone Rituximab TNB-486 Vincristine Sulfate | 0 | 2 |
| Rituximab + TNB-486 | Rituximab TNB-486 | 0 | 1 |
| TNB-486 | TNB-486 | 0 | 4 |
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