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Drug Name IAG933
Trade Name
Synonyms IAG 933|IAG-933
Drug Descriptions

IAG933 disrupts the interaction between yes-associated protein 1 (YAP) and the transcription factor TEAD, potentially leading to decreased YAP/TEAD-dependent gene expression and tumor growth inhibition (PMID: 38565920).

DrugClasses
CAS Registry Number NA
NCIT ID C185454

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capmatinib + IAG933 Capmatinib IAG933 0 0
Dabrafenib + IAG933 Dabrafenib IAG933 1 0
Dabrafenib + IAG933 + LTT462 Dabrafenib IAG933 LTT462 1 0
Dabrafenib + IAG933 + Trametinib Dabrafenib IAG933 Trametinib 1 0
IAG933 IAG933 0 1
IAG933 + JDQ443 IAG933 JDQ443 0 0
IAG933 + Lapatinib IAG933 Lapatinib 0 0
IAG933 + MRTX-1133 IAG933 MRTX-1133 0 0
IAG933 + Osimertinib IAG933 Osimertinib 0 0
IAG933 + RMC-7977 IAG933 RMC-7977 0 0


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