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Drug Name | Capmatinib |
Trade Name | Tabrecta |
Synonyms | INC280|INC-280|INCB028060|INCB28060|INCB 28060 |
Drug Descriptions |
Tabrecta (capmatinib) inhibits MET signaling and may induce cell death in tumors overexpressing MET or expressing constitutively activated MET (PMID: 31853265). Tabrecta (capmatinib) is FDA approved for use in patients with metastatic non-small cell lung cancer harboring MET exon 14 skipping mutations (FDA.gov). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 1029712-80-8 |
NCIT ID | C90564 |