LTT462
Drug Detail
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| Drug Name | LTT462 |
| Trade Name | |
| Synonyms | LTT 462|LTT-462|rineterkib |
| Drug Descriptions |
LTT462 inhibits ERK, resulting in decreased downstream signaling, and reduced ERK-dependent proliferation and survival of tumor cells (NCI Drug Dictionary). |
| DrugClasses | ERK Inhibitor (pan) 21 |
| CAS Registry Number | NA |
| NCIT ID | C126687 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Dabrafenib + IAG933 + LTT462 | Dabrafenib IAG933 LTT462 | 1 | 0 |
| Dabrafenib + LTT462 | Dabrafenib LTT462 | 0 | 1 |
| Dabrafenib + LTT462 + LXH 254 | Dabrafenib LTT462 LXH 254 | 0 | 1 |
| Dabrafenib + LTT462 + Spartalizumab | Dabrafenib LTT462 Spartalizumab | 0 | 1 |
| Dabrafenib + LTT462 + TNO155 | Dabrafenib LTT462 TNO155 | 0 | 1 |
| Dabrafenib + LTT462 + Trametinib | Dabrafenib LTT462 Trametinib | 0 | 1 |
| LTT462 | LTT462 | 0 | 1 |
| LTT462 + LXH 254 | LTT462 LXH 254 | 4 | 2 |
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