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Drug Name | AMX-818 |
Trade Name | |
Synonyms | AMX 818|AMX818 |
Drug Descriptions |
AMX-818 is a prodrug T-cell engager that targets CD3 and ERBB2 (HER2) which is activated in the tumor microenvironment, potentially resulting in activation of an immune response against ERBB2 (HER2)-expressing tumors and inhibition of tumor growth (Mol Cancer Ther 2021;20(12 Suppl):Abstract nr P193). |
DrugClasses | CD3 Antibody 103 HER2 (ERBB2) Antibody 76 |
CAS Registry Number | NA |
NCIT ID | C187696 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AMX-818 | AMX-818 | 0 | 1 |
AMX-818 + Pembrolizumab | AMX-818 Pembrolizumab | 0 | 1 |