PF-07799933
Drug Detail
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| Drug Name | PF-07799933 |
| Trade Name | |
| Synonyms | PF07799933|PF 07799933|ARRY440|ARRY 440|ARRY-440 |
| Drug Descriptions |
PF-07799933 inhibits BRAF mutations, including class 1, 2, and 3 mutations, which potentially leads to decreased downstream Erk signaling and inhibition of tumor growth (PMID: 38691346). |
| DrugClasses | BRAF Inhibitor 26 |
| CAS Registry Number | NA |
| NCIT ID | C191953 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Binimetinib + PF-07799933 | Binimetinib PF-07799933 | 4 | 1 |
| Cetuximab + PF-07799933 | Cetuximab PF-07799933 | 0 | 1 |
| PF-07799544 + PF-07799933 | PF-07799544 PF-07799933 | 0 | 1 |
| PF-07799933 | PF-07799933 | 9 | 1 |
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