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Drug Name TILT-123
Trade Name
Synonyms igrelimogene litadenorepvec|TILT 123|TILT123
Drug Descriptions

TILT-123 is an oncolytic adenovirus engineered to express cytokines TNF-alpha and IL-2, potentially leading to activation of the immune response, and inhibition of tumor growth when combined with immune checkpoint inhibitors (PMID: 33513935).

DrugClasses
CAS Registry Number NA
NCIT ID C175454

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + TILT-123 Avelumab TILT-123 0 1
Pembrolizumab + TILT-123 Pembrolizumab TILT-123 0 2
TILT-123 TILT-123 0 2


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