Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name ASP2138
Trade Name
Synonyms ASP-2138|ASP 2138
Drug Descriptions

ASP2138 is a bispecific antibody that targets Claudin 18.2 (CLDN18.2) expressed on tumor cells and CD3 on T-cells, which potentially leads to cytotoxic killing of tumor cells expressing CLDN18.2, enhanced antitumor immune response, and inhibition of tumor growth (Cancer Res (2023) 83 (7_Supplement): 2962).

DrugClasses CD3 Antibody 99 CLDN18.2 Antibody 19
CAS Registry Number NA
NCIT ID C187658

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ASP2138 ASP2138 0 1
ASP2138 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin ASP2138 Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
ASP2138 + Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab ASP2138 Fluorouracil Leucovorin Oxaliplatin Pembrolizumab 0 1
ASP2138 + Paclitaxel + Ramucirumab ASP2138 Paclitaxel Ramucirumab 0 1


Additional content available in CKB BOOST