AB521
Drug Detail
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| Drug Name | AB521 |
| Trade Name | |
| Synonyms | AB-521|AB 521|casdatifan |
| Drug Descriptions |
AB521 selectively inhibits HIF-2alpha, potentially resulting in downregulation of HIF-2alpha target genes and antitumor activity (Ann Oncol 33 (2022): S21). |
| DrugClasses | HIF2A Inhibitor 6 |
| CAS Registry Number | 2709069-30-5 |
| NCIT ID | C192674 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AB521 | AB521 | 0 | 1 |
| AB521 + Cabozantinib | AB521 Cabozantinib | 0 | 1 |
| AB521 + MEDI5752 | AB521 MEDI5752 | 0 | 1 |
| AB521 + Nivolumab + XL092 | AB521 Nivolumab XL092 | 0 | 1 |
| AB521 + XL092 | AB521 XL092 | 0 | 1 |
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