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| Drug Name | MTX-1000 |
| Trade Name | |
| Synonyms | MTX1000|MTX 1000 |
| Drug Descriptions |
MTX-1000 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2) antibody linked to exatecan, which upon internalization may result in tumor cell killing and decreased growth of ERBB2 (HER2)-expressing tumors (PMID: 36693125). |
| DrugClasses | HER2 (ERBB2) Antibody-Drug Conjugate 35 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| MTX-1000 | MTX-1000 | 0 | 0 |
| MTX-1000 + Talazoparib | MTX-1000 Talazoparib | 0 | 0 |
| MTX-1000 + VX-803 | MTX-1000 VX-803 | 0 | 0 |