Therapy Detail
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| Therapy Name | MTX-1000 + VX-803 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MTX-1000 | MTX1000|MTX 1000 | HER2 (ERBB2) Antibody-Drug Conjugate 31 | MTX-1000 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2) antibody linked to exatecan, which upon internalization may result in tumor cell killing and decreased growth of ERBB2 (HER2)-expressing tumors (PMID: 36693125). | |
| VX-803 | M4344|VX80|gartisertib | ATR Inhibitor 16 | VX-803 (M4344) is an inhibitor of ATR that is used in combination with radiation or chemotherapy (PMID: 30645202, PMID: 31836456). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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