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Drug Name | RO7425781 |
Trade Name | |
Synonyms | RO 7425781|RO-7425781|RG6234|RG-6234|RG 6234|Formitamig |
Drug Descriptions |
RO7425781 (RG6234) is a bispecific antibody that targets GPRC5D expressed on tumor cells and CD3 expressed on T-lymphocytes, potentially resulting in enhanced antitumor immune response and inhibition of tumor growth (Blood (2022) 140 (Supplement 1): 10137-10139, Blood (2022) 140 (Supplement 1): 2091-2092). |
DrugClasses | CD3 Antibody 99 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carfilzomib + RO7425781 | Carfilzomib RO7425781 | 0 | 1 |
Daratumumab + RO7425781 | Daratumumab RO7425781 | 0 | 1 |
RO7425781 | RO7425781 | 0 | 2 |