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Drug Name TROP2-CAR/IL15-transduced CBNK cells
Trade Name
Synonyms TROP2-CAR-NK cells|TROP2-CAR-engineered IL15-transduced Cord Blood-derived NKs
Drug Descriptions

TROP2-CAR/IL15-transduced CBNK cells are cord blood-derived natural killer (NK) cells engineered to express IL15 and a chimeric antigen receptor (CAR) that targets TROP2, which potentially induce cytotoxicity against tumor cells expressing TROP2 (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C200344

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + TROP2-CAR/IL15-transduced CBNK cells Cetuximab TROP2-CAR/IL15-transduced CBNK cells 0 1
Cyclophosphamide + Fludarabine + Rimiducid + TROP2-CAR/IL15-transduced CBNK cells Cyclophosphamide Fludarabine Rimiducid TROP2-CAR/IL15-transduced CBNK cells 0 0
TROP2-CAR/IL15-transduced CBNK cells TROP2-CAR/IL15-transduced CBNK cells 0 2


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