Darlifarnib
Drug Detail
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| Drug Name | Darlifarnib |
| Trade Name | |
| Synonyms | KO 2806|KO2806|KO-2806 |
| Drug Descriptions |
Darlifarnib (KO-2806) is a farnesyltransferase inhibitor, which may inhibit the Mtor pathway, leading to cell cycle arrest and inhibition of cell growth (Mol Cancer Ther (2023) 22 (12_Supplement): B024). |
| DrugClasses | Farnesyltransferase Inhibitor 4 |
| CAS Registry Number | 3065226-39-0 |
| NCIT ID | C201577 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Adagrasib + Darlifarnib | Adagrasib Darlifarnib | 0 | 1 |
| Cabozantinib + Darlifarnib | Cabozantinib Darlifarnib | 0 | 1 |
| Darlifarnib | Darlifarnib | 0 | 1 |
| Darlifarnib + MRTX-1133 | Darlifarnib MRTX-1133 | 0 | 0 |
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