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Drug Name | AZD0901 |
Trade Name | |
Synonyms | AZD-0901|AZD 0901|CMG901|CM-G901|CM G901 |
Drug Descriptions |
AZD0901 is an antibody-drug conjugate (ADC) comprising an anti-CLDN18.2 antibody linked to the anti-microtubule agent monomethyl auristatin E (MMAE), which may induce antibody-dependent cellular cytotoxicity (ADCC) and inhibit tumor growth (PMID: 39232496). |
DrugClasses | CLDN18.2 Antibody 19 |
CAS Registry Number | NA |
NCIT ID | C180413 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD0901 | AZD0901 | 0 | 2 |
AZD0901 + Fluorouracil | AZD0901 Fluorouracil | 0 | 1 |
AZD0901 + Gemcitabine | AZD0901 Gemcitabine | 0 | 1 |
AZD0901 + Irinotecan | AZD0901 Irinotecan | 0 | 1 |
AZD0901 + Leucovorin | AZD0901 Leucovorin | 0 | 1 |
AZD0901 + Liposomal irinotecan | AZD0901 Liposomal irinotecan | 0 | 1 |
AZD0901 + unspecified PD-1 antibody | AZD0901 unspecified PD-1 antibody | 0 | 0 |