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Drug Name | Darleukin |
Trade Name | |
Synonyms | L19-IL2|L19IL2|bifikafusp alfa |
Drug Descriptions |
Darleukin is an immunocytokine comprising a recombinant antibody targeting the ED-B domain of fibronectin fused to human IL-2, which delivers the cytokine to developing blood vessels in the tumor and may induce an anti-tumor immune response (PMID: 11861281). |
DrugClasses | |
CAS Registry Number | 1957239-90-5 |
NCIT ID | C90546 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
[177]Lu-OncoFAP-23 + Darleukin | Darleukin [177]Lu-OncoFAP-23 | 0 | 1 |
Darleukin | Darleukin | 0 | 0 |
Darleukin + Pembrolizumab | Darleukin Pembrolizumab | 0 | 1 |