BMS-986504
Drug Detail
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| Drug Name | BMS-986504 |
| Trade Name | |
| Synonyms | BMS 986504|BMS986504 |
| Drug Descriptions |
BMS-986504 binds to the PRMT5-MTA complex and inhibits PRMT5 activity, which potentially enhances antitumor immune response and induces killing of tumor cells with deletion of MTAP (Cancer Immunol Res (2024) 12 (10_Supplement): B011, Eur J Cancer 211 (2024): 114537). |
| DrugClasses | PRMT5 Inhibitor 21 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BMS-986504 | BMS-986504 | 0 | 3 |
| BMS-986504 + Gemcitabine + Nab-paclitaxel | BMS-986504 Gemcitabine Nab-paclitaxel | 0 | 1 |
| BMS-986504 + Pembrolizumab | BMS-986504 Pembrolizumab | 0 | 1 |
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