M0324
Drug Detail
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| Drug Name | M0324 |
| Trade Name | |
| Synonyms | M-0324|M 0324 |
| Drug Descriptions |
M0324 is a MUC1-conditional CD40 agonist comprising an antibody targeting MUC1 and two heavy-chain variable domains that bind to CD40, which potentially induces antitumor immune activity against MUC1-expressing tumors (Cancer Res (2025) 85 (8_Supplement_2): ND12). |
| DrugClasses | CD40 Antibody 16 MUC1 Antibody 8 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Fluorouracil + Irinotecan + Leucovorin + M0324 + Oxaliplatin | Fluorouracil Irinotecan Leucovorin M0324 Oxaliplatin | 0 | 1 |
| M0324 | M0324 | 0 | 1 |
| M0324 + Pembrolizumab | M0324 Pembrolizumab | 0 | 1 |
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