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Drug Name | BI2536 |
Trade Name | |
Synonyms | BI 2536|BI-2536 |
Drug Descriptions |
BI2536 inhibits polo-like kinase 1 (PLK1), which disrupts mitosis and induces apoptosis in tumor cells (PMID: 30414309, PMID: 32486290). |
DrugClasses | PLK1 Inhibitor 18 |
CAS Registry Number | 755038-02-9 |
NCIT ID | C49091 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BI2536 | BI2536 | 1 | 0 |
BI2536 + Metformin | BI2536 Metformin | 0 | 0 |
BI2536 + PD-0325901 | BI2536 PD-0325901 | 0 | 0 |
BI2536 + PLX4720 | BI2536 PLX4720 | 1 | 0 |