BI2536
Drug Detail
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| Drug Name | BI2536 |
| Trade Name | |
| Synonyms | BI 2536|BI-2536 |
| Drug Descriptions |
BI2536 inhibits polo-like kinase 1 (PLK1), which disrupts mitosis and induces apoptosis in tumor cells (PMID: 30414309, PMID: 32486290). |
| DrugClasses | PLK1 Inhibitor 18 |
| CAS Registry Number | 755038-02-9 |
| NCIT ID | C49091 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BI2536 | BI2536 | 1 | 0 |
| BI2536 + Metformin | BI2536 Metformin | 0 | 0 |
| BI2536 + Mirdametinib | BI2536 Mirdametinib | 0 | 0 |
| BI2536 + PLX4720 | BI2536 PLX4720 | 1 | 0 |
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