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| Drug Name | Mirdametinib |
| Trade Name | Gomekli |
| Synonyms | PD0325901|PD 0325901|PD-901|PD-0325901 |
| Drug Descriptions |
Gomekli (mirdametinib), a derivative of CI-1040, is a pan-MEK inhibitor, which inhibits activation of MAPK/ERK resulting in decreased tumor cell proliferation (PMID: 18952427, PMID: 32147669). Gomekli (mirdametinib) is FDA-approved for use in adult and pediatric patients 2 years and older with neurofibromatosis type 1 who have symptomatic plexiform neurofibromas (FDA.gov). |
| DrugClasses | MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24 |
| CAS Registry Number | 391210-10-9 |
| NCIT ID | C52195 |
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