XL888
Drug Detail
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| Drug Name | XL888 |
| Trade Name | |
| Synonyms | XL-888 |
| Drug Descriptions |
XL888 inhibits HSP90, resulting in degradation of HSP90 client proteins, and potentially leading to decreased tumor growth (PMID: 23538902, PMID: 22877636, PMID: 29674508). |
| DrugClasses | HSP90 Inhibitor 35 |
| CAS Registry Number | 1149705-71-4 |
| NCIT ID | C79835 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cobimetinib + Vemurafenib + XL888 | Cobimetinib Vemurafenib XL888 | 0 | 1 |
| Pembrolizumab + XL888 | Pembrolizumab XL888 | 0 | 1 |
| Vemurafenib + XL888 | Vemurafenib XL888 | 1 | 1 |
| XL888 | XL888 | 1 | 0 |
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