CUDC-907
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| Drug Name | CUDC-907 |
| Trade Name | |
| Synonyms | Fimepinostat |
| Drug Descriptions |
CUDC-907 (fimepinostat) is a dual PI3K and HDAC inhibitor, which prevents activation of the PI3K-AKT-mTOR signal transduction pathway, inhibits tumor cell growth, and promotes apoptosis in cancer cells (PMID: 22693356, PMID: 32459381). |
| DrugClasses | HDAC Inhibitor 45 PI3K Inhibitor (Pan) 42 |
| CAS Registry Number | 1339928-25-4 |
| NCIT ID | C104008 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD1480 + CUDC-907 | AZD1480 CUDC-907 | 1 | 0 |
| Bendamustine + CUDC-907 + Rituximab | Bendamustine CUDC-907 Rituximab | 0 | 1 |
| CUDC-907 | CUDC-907 | 5 | 6 |
| CUDC-907 + Gilteritinib | CUDC-907 Gilteritinib | 1 | 0 |
| CUDC-907 + Rituximab | CUDC-907 Rituximab | 0 | 1 |
| CUDC-907 + Venetoclax | CUDC-907 Venetoclax | 0 | 1 |
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