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| Drug Name | Gilteritinib |
| Trade Name | Xospata |
| Synonyms | ASP2215 |
| Drug Descriptions |
Xospata (gilteritinib) is a small molecule inhibitor of FLT3 and AXL that has activity against FLT3-ITD, FLT3 F691L, and FLT3 D835 mutations, potentially resulting in decreased tumor growth (J Clin Oncol 32:5s, 2014 (suppl; abstr 7070), PMID: 25891481). Xospata (gilteritinib) is FDA approved for use in patients with relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation (ITD, D835X, and I836X) (FDA.gov). |
| DrugClasses | AXL Inhibitor 30 FLT3 Inhibitor 69 |
| CAS Registry Number | 1254053-43-4 |
| NCIT ID | C116722 |
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