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| Drug Name | Necitumumab |
| Trade Name | Portrazza |
| Synonyms | IMC-11F8 |
| Drug Descriptions |
Portrazza (necitumumab) is a fully human IgG1 mAb targeting EGFR, leading to the inhibition of downstream targets in the EGFR pathway, and thereby inhibiting cellular proliferation and invasion (PMID: 21154125). Portrazza (necitumumab) is approved for patients with metastatic squamous non-small cell lung cancer (FDA.gov). |
| DrugClasses | EGFR Antibody 60 |
| CAS Registry Number | 906805-06-9 |
| NCIT ID | C88281 |
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