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Drug Name | Brigatinib |
Trade Name | Alunbrig |
Synonyms | AP26113 |
Drug Descriptions |
Alunbrig (brigatinib) is a multi-kinase inhibitor with selected activity against ALK, ROS1 fusions, FLT3, IGF1R and mutant EGFR, potentially resulting in decreased tumor growth (PMID: 27780853). Alunbrig (brigatinib) is FDA approved for use in patients with ALK-positive metastatic non-small cell lung cancer (FDA.gov). |
DrugClasses | ALK Inhibitor 32 EGFR Inhibitor (Pan) 62 FLT3 Inhibitor 69 IGF-1R Inhibitor 17 ROS1 Inhibitor 20 |
CAS Registry Number | 1197953-54-0 |
NCIT ID | C98831 |