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| Drug Name | Pralatrexate |
| Trade Name | FOLOTYN |
| Synonyms | |
| Drug Descriptions |
Pralatrexate is folate analogue inhibitor of dihydrofolate reductase that is selective for cells expressing RFC-1 (which may be overexpressed on cancer cells). Pralatrexate causes depletion of nucleotide precursors; inhibition of DNA, RNA and protein synthesis; and apoptotic tumor cell death (NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | 146464-95-1 |
| NCIT ID | C2250 |
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