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| Drug Name | Brentuximab vedotin |
| Trade Name | Adcetris |
| Synonyms | SGN-35 |
| Drug Descriptions |
Adcetris (brentuximab vedotin) is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody targeting CD30 linked to the tubulin-binding drug MMAE, which binds CD30-expressing cells and disrupts microtubule polymerization, potentially resulting in decreased tumor growth (PMID: 22684302). Adcetris (brentuximab vedotin) is FDA approved for Hodgkin lymphoma, anaplastic large cell lymphoma, CD30-expressing mycosis fungoides, and in combination with chemotherapy in other CD30-expressing peripheral T-cell lymphomas (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 914088-09-8 |
| NCIT ID | C66944 |
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