131I-MIBG
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| Drug Name | 131I-MIBG |
| Trade Name | Azedra |
| Synonyms | I131 Metaiodobenzylguanidine iodine|iobenguane I 131 |
| Drug Descriptions |
Azedra (iobenguane I 131) is a norepinephrine-like molecule labeled with radioactive I 131, which can be used to image or eliminate tumor cells overexpressing norepinephrine transporters (PMID: 25874239). Azedra (iobenguane I 131) is FDA approved for use in adult and pediatric patients 12 years and older with iobenguane scan positive pheochromocytoma or paraganglioma (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 77679-27-7 |
| NCIT ID | C82344 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| 131I-MIBG | 131I-MIBG | 0 | 5 |
| 131I-MIBG + Dinutuximab + Sargramostim | 131I-MIBG Dinutuximab Sargramostim | 0 | 1 |
| 131I-MIBG + Dinutuximab + Sargramostim + Vorinostat | 131I-MIBG Dinutuximab Sargramostim Vorinostat | 0 | 1 |
| 131I-MIBG + Irinotecan + Vincristine Sulfate | 131I-MIBG Irinotecan Vincristine Sulfate | 0 | 1 |
| 131I-MIBG + Lutetium Lu 177 dotatate | 131I-MIBG Lutetium Lu 177 dotatate | 0 | 1 |
| 131I-MIBG + Vorinostat | 131I-MIBG Vorinostat | 0 | 2 |
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