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Drug Name | GDC-0084 |
Trade Name | |
Synonyms | GDC0084|Paxalisib |
Drug Descriptions |
Paxalisib (GDC-0084) is a dual pan-PI3K and mTOR inhibitor, which prevents cell proliferation and potentially inhibits tumor growth (PMID: 22619466, PMID: 32269051, PMID: 31937616). |
DrugClasses | mTOR Inhibitor 51 PI3K Inhibitor (Pan) 42 |
CAS Registry Number | 1382979-44-3 |
NCIT ID | C116877 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GDC-0084 | GDC-0084 | 1 | 6 |
GDC-0084 + Irinotecan + Temozolomide | GDC-0084 Irinotecan Temozolomide | 0 | 1 |
GDC-0084 + Metformin | GDC-0084 Metformin | 0 | 1 |
GDC-0084 + ONC201 | GDC-0084 ONC201 | 0 | 1 |
GDC-0084 + Trastuzumab | GDC-0084 Trastuzumab | 0 | 1 |