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Drug Name | Napabucasin |
Trade Name | |
Synonyms | BB608|BBI608|BBI-608|GB201|GB-201|GB 201 |
Drug Descriptions |
Napabucasin (BBI608) is a small molecule inhibitor of cancer stemness that reduces activated Stat3 signaling, which is often activated by FGFRs, thereby decreasing proliferation of cancer stem cells, and possibly resulting in decreased cancer metastasis (PMID: 25605917, PMID: 23935373, PMID: 32694160). |
DrugClasses | STAT3 Inhibitor 26 |
CAS Registry Number | 83280-65-3 |
NCIT ID | C96429 |