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Drug Name Ravoxertinib
Trade Name
Synonyms GDC-0994
Drug Descriptions

Ravoxertinib (GDC-0994) is a small molecule inhibitor of ERK1 and ERK2, which may decrease tumor growth (Cancer Res October 1, 2014 74:DDT02-03, PMID: 32311798, PMID: 31848189).

DrugClasses ERK Inhibitor (pan) 21
CAS Registry Number 1453848-26-4
NCIT ID C107241

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cobimetinib + Ravoxertinib Cobimetinib Ravoxertinib 0 0
Ravoxertinib Ravoxertinib 11 2
Ravoxertinib + Vemurafenib Ravoxertinib Vemurafenib 1 0


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