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Drug Name | Ravoxertinib |
Trade Name | |
Synonyms | GDC-0994 |
Drug Descriptions |
Ravoxertinib (GDC-0994) is a small molecule inhibitor of ERK1 and ERK2, which may decrease tumor growth (Cancer Res October 1, 2014 74:DDT02-03, PMID: 32311798, PMID: 31848189). |
DrugClasses | ERK Inhibitor (pan) 21 |
CAS Registry Number | 1453848-26-4 |
NCIT ID | C107241 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cobimetinib + Ravoxertinib | Cobimetinib Ravoxertinib | 0 | 0 |
Ravoxertinib | Ravoxertinib | 11 | 2 |
Ravoxertinib + Vemurafenib | Ravoxertinib Vemurafenib | 1 | 0 |