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Drug Name | Mavelertinib |
Trade Name | |
Synonyms | PF-06747775 |
Drug Descriptions |
Mavelertinib (PF-06747775) is a specific inhibitor of EGFR T790M, which causes cell death in EGFR T790M-positive tumor cells, while sparing wild-type EGFR (PMID: 30718357). |
DrugClasses | EGFR Inhibitor 3rd gen 26 |
CAS Registry Number | 1776112-90-3 |
NCIT ID | C120307 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Avelumab + Mavelertinib | Avelumab Mavelertinib | 0 | 1 |
JBJ-04-125-02 + Mavelertinib | JBJ-04-125-02 Mavelertinib | 0 | 0 |
Mavelertinib | Mavelertinib | 0 | 1 |
Mavelertinib + Palbociclib | Mavelertinib Palbociclib | 0 | 1 |