X4P-001
Drug Detail
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| Drug Name | X4P-001 |
| Trade Name | |
| Synonyms | Mavorixafor|X4P-001-IO|AMD-070|AMD-11070|AMD11070 |
| Drug Descriptions |
Mavorixafor (X4P-001), is a CXCR4 antagonist, which blocks the binding of CXCL12 to prevent metastasis and may activate cytotoxic T-lymphocytes (PMID: 23538388). |
| DrugClasses | CXCR4 Inhibitor 15 |
| CAS Registry Number | 558447-26-0 |
| NCIT ID | C126660 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Axitinib + X4P-001 | Axitinib X4P-001 | 0 | 0 |
| Ibrutinib + X4P-001 | Ibrutinib X4P-001 | 0 | 1 |
| Nivolumab + X4P-001 | Nivolumab X4P-001 | 0 | 1 |
| Pembrolizumab + X4P-001 | Pembrolizumab X4P-001 | 0 | 1 |
| X4P-001 | X4P-001 | 0 | 1 |
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