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| Drug Name | Xevinapant |
| Trade Name | |
| Synonyms | AT-406|SM-406|Debio1143|Debio-1143|Debio 1143 |
| Drug Descriptions |
Xevinapant (debio 1143) is a SMAC mimetic, which antagonizes Inhibitor of Apoptosis Protein (IAP) family proteins, resulting in increased tumor cell apoptosis, decreased tumor growth (PMID: 21443232), and may reverse immunosuppression (PMID: 30352911, PMID: 32758455). |
| DrugClasses | SMAC Mimetic 8 |
| CAS Registry Number | 1071992-99-8 |
| NCIT ID | C90574 |
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