Tebentafusp
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| Drug Name | Tebentafusp |
| Trade Name | Kimmtrak |
| Synonyms | ImmTAC-gp100|Tebentafusp-tebn|IMCgp100 |
| Drug Descriptions |
Kimmtrak (tebentafusp) is a gp100 antigen-specific human T-cell receptor (TCR) linked to an anti-CD3 antibody fragment, which activates cytotoxic immune response against gp100-expressing tumor cells (PMID: 24531387, PMID: 31336704, PMID: 32816891). Kimmtrak (tebentafusp) is FDA approved for use in HLA-A*2:01-positive metastatic or unresectable uveal melanoma patients (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 1874157-95-5 |
| NCIT ID | C94208 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldesleukin + Tebentafusp | Aldesleukin Tebentafusp | 0 | 1 |
| Carmustine + Tebentafusp | Carmustine Tebentafusp | 0 | 1 |
| Doxorubicin + Tebentafusp | Doxorubicin Tebentafusp | 0 | 1 |
| Pembrolizumab + Tebentafusp | Pembrolizumab Tebentafusp | 0 | 1 |
| Roginolisib + Tebentafusp | Roginolisib Tebentafusp | 0 | 1 |
| Sargramostim + Tebentafusp | Sargramostim Tebentafusp | 0 | 1 |
| Tebentafusp | Tebentafusp | 0 | 13 |
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