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Drug Name | Tomivosertib |
Trade Name | |
Synonyms | eFT508|EFT-508 |
Drug Descriptions |
Tomivosertib (eFT508) inhibits MNK1/2 and phosphorylation of eIF4E, which may lead to impaired translation of CD274 (PD-L1), potentially resulting in decreased tumor cell proliferation and inhibition of tumor growth (PMID: 30643286, PMID: 34012509). |
DrugClasses | MNK1/2 Inhibitor 3 |
CAS Registry Number | 1849590-01-7 |
NCIT ID | C125062 |