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Drug Name | Domatinostat |
Trade Name | |
Synonyms | 4SC-202 |
Drug Descriptions |
Domatinostat (4SC-202) is a class I histone deacetylase inhibitor that inhibits proliferation and induces apoptosis in tumor cells (PMID: 26773495, PMID: 30347469, PMID: 32210076). |
DrugClasses | HDAC Inhibitor 45 |
CAS Registry Number | 910462-43-0 |
NCIT ID | C96797 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Avelumab + Domatinostat | Avelumab Domatinostat | 0 | 2 |
Domatinostat | Domatinostat | 0 | 0 |
Domatinostat + Pembrolizumab | Domatinostat Pembrolizumab | 0 | 1 |