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Drug Name | AdV-tk |
Trade Name | |
Synonyms | Aglatimagene besadenovec|GliAtak|ProstAtak|CAN-2409|CAN2409|Virafir |
Drug Descriptions |
ADV-tk (aglatimagene besadenovec) is an engineered adenoviral vector expressing the herpes simplex virus thymidine kinase that sensitizes tumor cells to therapy with acyclic guanosine analogues (PMID: 26843484, PMID: 30883662). |
DrugClasses | |
CAS Registry Number | 1621271-62-2 |
NCIT ID | C73996 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Acyclovir + AdV-tk | Acyclovir AdV-tk | 0 | 1 |
AdV-tk | AdV-tk | 0 | 2 |
AdV-tk + Nivolumab | AdV-tk Nivolumab | 0 | 1 |
AdV-tk + Valacyclovir | AdV-tk Valacyclovir | 0 | 6 |