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Drug Name | RVU120 |
Trade Name | |
Synonyms | SEL120|SEL 120-34|SEL120-34A|RVU 120|RVU-120 |
Drug Descriptions |
RVU120 (SEL120) selectively inhibits CDK8, resulting in decreased STAT5 and STAT1 phosphorylation and downstream signaling, and potentially leading to reduced tumor cell growth (PMID: 28422713). |
DrugClasses | CDK8 Inhibitor 5 |
CAS Registry Number | 1609522-33-9 |
NCIT ID | C165747 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
RVU120 | RVU120 | 0 | 3 |
RVU120 + Venetoclax | RVU120 Venetoclax | 0 | 1 |