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Drug Name | DS-3201b |
Trade Name | |
Synonyms | DS-3201|Valemetostat Tosylate |
Drug Descriptions |
DS-3201b inhibits EZH1 and EZH2, resulting in decreased H3K27 trimethylation and potentially leading to decreased tumor growth (Blood 2017 130:2073, PMID: 30658046). |
DrugClasses | EZH1 inhibitor 5 EZH2 inhibitor 20 |
CAS Registry Number | 1809336-93-3 |
NCIT ID | C168589 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + DS-3201b | Atezolizumab Bevacizumab DS-3201b | 0 | 1 |
Datopotamab deruxtecan + DS-3201b | DS-3201b Datopotamab deruxtecan | 0 | 1 |
DS-3201b | DS-3201b | 0 | 5 |
DS-3201b + Ipilimumab | DS-3201b Ipilimumab | 0 | 1 |
DS-3201b + Irinotecan | DS-3201b Irinotecan | 0 | 1 |
DS-3201b + Lenalidomide + Rituximab | DS-3201b Lenalidomide Rituximab | 0 | 1 |
DS-3201b + Pembrolizumab | DS-3201b Pembrolizumab | 0 | 1 |
DS-3201b + Trastuzumab deruxtecan | DS-3201b Trastuzumab deruxtecan | 0 | 2 |