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| Drug Name | Darolutamide |
| Trade Name | Nubeqa |
| Synonyms | BAY1841788|ODM-201 |
| Drug Descriptions |
Nubeqa (darolutamide) is an androgen receptor antagonist that binds to and prevents nuclear translocation of the androgen receptor, thereby inhibiting expression of genes downstream of androgen receptor signaling that regulate proliferation of prostate cancer cells (PMID: 28490267). Nubeqa (darolutamide) is FDA approved for use in patients with non-metastatic castration-resistant prostate cancer, and in combination with docetaxel in patients with metastatic hormone-sensitive prostate cancer (FDA.gov). |
| DrugClasses | Hormone - Anti-androgens 54 |
| CAS Registry Number | 1297538-32-9 |
| NCIT ID | C104748 |
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