Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Zenocutuzumab
Trade Name
Synonyms MCLA-128|MCLA128|MCLA 128
Drug Descriptions

Zenocutuzumab (MCLA-128) is a bispecific antibody that targets Erbb2 (Her2) and Erbb3, resulting in antibody-dependent cell-mediated cytotoxicity against tumor cells (Cancer Res 2016;76(14 Suppl):Abstract nr CT050, PMID: 32054397).

DrugClasses HER2 (ERBB2) Antibody 76 HER3 (ERBB3) Antibody 23
CAS Registry Number 1969309-56-5
NCIT ID C152948

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Zenocutuzumab Abiraterone Zenocutuzumab 0 1
Afatinib + Zenocutuzumab Afatinib Zenocutuzumab 0 1
Anastrozole + Zenocutuzumab Anastrozole Zenocutuzumab 0 1
Enzalutamide + Zenocutuzumab Enzalutamide Zenocutuzumab 0 1
Exemestane + Zenocutuzumab Exemestane Zenocutuzumab 0 1
Fulvestrant + Zenocutuzumab Fulvestrant Zenocutuzumab 0 1
Letrozole + Zenocutuzumab Letrozole Zenocutuzumab 0 1
Trastuzumab + Vinorelbine + Zenocutuzumab Trastuzumab Vinorelbine Zenocutuzumab 0 1
Trastuzumab + Zenocutuzumab Trastuzumab Zenocutuzumab 0 1
Zenocutuzumab Zenocutuzumab 0 1


Additional content available in CKB BOOST