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Drug Name C188-9
Trade Name
Synonyms TTI101|TTI-101|TTI 101
Drug Descriptions

C188-9 (TTI-101) is a small molecule that binds to STAT3 and inhibits signaling, potentially resulting in tumor cell death (PMID: 27027445, PMID: 32475130).

DrugClasses STAT3 Inhibitor 26
CAS Registry Number 432001-19-9
NCIT ID C151932

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + C188-9 Atezolizumab Bevacizumab C188-9 0 1
C188-9 C188-9 0 4
C188-9 + Fulvestrant C188-9 Fulvestrant 0 1
C188-9 + Palbociclib C188-9 Palbociclib 0 1
C188-9 + Pembrolizumab C188-9 Pembrolizumab 0 1
C188-9 + Ribociclib C188-9 Ribociclib 0 1


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