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Drug Name | C188-9 |
Trade Name | |
Synonyms | TTI101|TTI-101|TTI 101 |
Drug Descriptions |
C188-9 (TTI-101) is a small molecule that binds to STAT3 and inhibits signaling, potentially resulting in tumor cell death (PMID: 27027445, PMID: 32475130). |
DrugClasses | STAT3 Inhibitor 26 |
CAS Registry Number | 432001-19-9 |
NCIT ID | C151932 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + C188-9 | Atezolizumab Bevacizumab C188-9 | 0 | 1 |
C188-9 | C188-9 | 0 | 4 |
C188-9 + Fulvestrant | C188-9 Fulvestrant | 0 | 1 |
C188-9 + Palbociclib | C188-9 Palbociclib | 0 | 1 |
C188-9 + Pembrolizumab | C188-9 Pembrolizumab | 0 | 1 |
C188-9 + Ribociclib | C188-9 Ribociclib | 0 | 1 |