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Drug Name | Tisagenlecleucel |
Trade Name | Kymriah |
Synonyms | CTL019 |
Drug Descriptions |
Kymriah (tisagenlecleucel) is a preparation of autologous T-lymphocytes engineered to express chimeric antigen receptors targeting CD19-positive cells, resulting in anti-tumor immune response (J Clin Oncol 35, 2017 (suppl; abstr 10523)). Kymriah (tisagenlecleucel) is FDA approved for pediatric and young adult patients with B-cell precursor acute lymphoblastic leukemia, adult patient with relapsed or refractory large B-cell lymphoma, and adult patients with relapsed or refractory follicular lymphoma (FDA.gov). |
DrugClasses | CD19 Immune Cell Therapy 62 |
CAS Registry Number | 1823078-37-0 |
NCIT ID | C102758 |